Representative trajectory illustrating Q277 from a single chain (cyan carbon atoms) and the surrounding residues (from top right and clockwise: E412, L414, E80, and E417; gray carbon atoms) in the WT cASIC1. Q277 is generally kept in a stable conformation to hydrogen bond to E80Oε and L414O. E80 is deprotonated, while E412 and E417 are protonated. The animation shows 100 ns of simulation time. Non-polar hydrogen atoms are omitted. Playback speed, 3 ns/s.
