Video 1.

Fluorescently labeled mAb signal in fetal and maternal tissues via whole body hyperspectral imaging. Experimental set up as described in Fig. S1. Left video shows a naïve control dam that did not receive fluorescent mAb, right video shows dam administered AF488-conjugated UB-621. Playback speed is 10 frames/s. Please note that this is not live imaging so the playback speed is not related to time during a longitudinally assessed process.


Maternally transferred mAbs protect neonatal mice from HSV-induced mortality and morbidity

Iara M. Backes, Brook K. Byrd, Matthew D. Slein, Chaya D. Patel, Sean A. Taylor, Callaghan R. Garland, Scott W. MacDonald, Alejandro B. Balazs, Scott C. Davis, Margaret E. Ackerman, and David A. Leib

DOI: 10.1084/jem.20220110
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