Video 7.

B cells resolve focal neutrophil inflammation in vivo. Related to Fig. 6. C57BL/6 or Ighm−/− mice were i.t. treated with zymosan-coated beads (106) or sterile PBS. Lung intravital microscopy was performed at 4 h and 24 h after stimulation, and neutrophil recruitment and B cell margination were assessed. Playback speed is 30 frames/s, 10 min actual imaging time per segment.


Marginating transitional B cells modulate neutrophils in the lung during inflammation and pneumonia

John Podstawka, Sarthak Sinha, Carlos H. Hiroki, Nicole Sarden, Elise Granton, Elodie Labit, Jung Hwan Kim, Graciela Andonegui, Yuefei Lou, Brendan D. Snarr, Donald C. Sheppard, Nicole L. Rosin, Jeff Biernaskie, and Bryan G. Yipp

DOI: 10.1084/jem.20210409
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