Video 2.

Video of adult Itgb8ΔCNS mouse with severe spasticity and uncoordinated movements, unkempt appearance, and kyphosis.

Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction

Thomas D. Arnold, Carlos O. Lizama, Kelly M. Cautivo, Nicolas Santander, Lucia Lin, Haiyan Qiu, Eric J. Huang, Chang Liu, Yoh-suke Mukouyama, Louis F. Reichardt, Ann C. Zovein, and Dean Sheppard

DOI: 10.1084/jem.20181290