Dynamics of CLR-RAMP2-AM complexes (blue, hCLR(V205del); orange, wild-type hCLR) following REMC simulations at 300 K. There is a progressive unfolding of the hCLR(V205del) which is not seen with wild-type.
Duncan I. Mackie, Fuad Al Mutairi, Reema B. Davis, Daniel O. Kechele, Natalie R. Nielsen, Joshua C. Snyder, Marc G. Caron, Harvey J. Kliman, Jonathan S. Berg, John Simms, David R. Poyner, and Kathleen M. Caron
