Video 1.

Spontaneously active astrocytes in the hippocampus of an APPPS1 mouse. Astrocytes were transfected with AAV encoding the fluorescent calcium indicator GCaMP6f under the astrocytic GfaABC1D promoter. The traces of astrocytic signals in this video are shown in Fig. 3 C.

P2Y1 receptor blockade normalizes network dysfunction and cognition in an Alzheimer’s disease model

Nicole Reichenbach, Andrea Delekate, Björn Breithausen, Kevin Keppler, Stefanie Poll, Theresa Schulte, Jan Peter, Monika Plescher, Jan N. Hansen, Nelli Blank, Armin Keller, Martin Fuhrmann, Christian Henneberger, Annett Halle, and Gabor C. Petzold

DOI: 10.1084/jem.20171487