Video 1.

Congregation of Tfh cells and B cells at the T–B border in response to immunization. Dynamics of DsRed⁺ OT-II T cells (red), CFP⁺ ICAM-1/2^+/+ B1-8^hi B cells (blue), and ICAM-1/2^−/− CFSE-labeled B1-8^hi B cells (green) at the border between the B and T zones of a popliteal lymph node, 2 d after immunization with NP-OVA. Bar, 20 µm.

ICAMs support B cell interactions with T follicular helper cells and promote clonal selection

Irina Zaretsky, Ofir Atrakchi, Roei D. Mazor, Liat Stoler-Barak, Adi Biram, Sara W. Feigelson, Alexander D. Gitlin, Britta Engelhardt, and Ziv Shulman

DOI: 10.1084/jem.20171129