Video 10.

Differently labeled OVA_323–339-pulsed BMDCs were pretreated with control or CCL22 siRNA 18 h before injection into the footpad of OT-II-Foxp3-GFP mice. The footpad-draining lymph node was imaged by two-photon microscopy (blue, control DCs; red, CCL22-deficient DCs; green, FoxP3⁺ cells).

CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes

Moritz Rapp, Maximilian W.M. Wintergerst, Wolfgang G. Kunz, Viola K. Vetter, Max M.L. Knott, Dominik Lisowski, Sascha Haubner, Stefan Moder, Raffael Thaler, Stephan Eiber, Bastian Meyer, Natascha Röhrle, Ignazio Piseddu, Simon Grassmann, Patrick Layritz, Benjamin Kühnemuth, Susanne Stutte, Carole Bourquin, Ulrich H. von Andrian, Stefan Endres, and David Anz

DOI: 10.1084/jem.20170277