Video 1.

Heightened Fascin-1 accumulation at the site of T reg cell–BMDC contacts. 3D rending of SIM stacks of a T reg cell–DC couple shown in Fig. 4 C. Notice the clustering of Fascin-1 at the deeply intermingled interface between the two cells. This experiment was independently performed three times.


Strong adhesion by regulatory T cells induces dendritic cell cytoskeletal polarization and contact-dependent lethargy

Jiahuan Chen, Anutosh Ganguly, Ashley D. Mucsi, Junchen Meng, Jiacong Yan, Pascal Detampel, Fay Munro, Zongde Zhang, Mei Wu, Aswin Hari, Melanie D. Stenner, Wencheng Zheng, Paul Kubes, Tie Xia, Matthias W. Amrein, Hai Qi, and Yan Shi

DOI: 10.1084/jem.20160620
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