Video 8.

The trajectory of the last 80 ns of FcγRIIB-I232T TM helix in POPC. The C terminus of the helix was moved to the center of the lower leaflet. The video is shown at 30 FPS.

Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupus-associated polymorphism FcγRIIB-T232

Liling Xu, Mengdie Xia, Jun Guo, Xiaolin Sun, Hua Li, Chenguang Xu, Xiaomei Gu, Haowen Zhang, Junyang Yi, Yan Fang, Hengyi Xie, Jing Wang, Zhixun Shen, Boxin Xue, Yujie Sun, Tobias Meckel, Ying-Hua Chen, Zhibin Hu, Zhanguo Li, Chenqi Xu, Haipeng Gong, and Wanli Liu

DOI: 10.1084/jem.20160528