DC movement in vehicle-treated CD11c-YFP mice in the steady state skin. A representative video showing DC movement in the steady state skin of vehicle-treated CD11c-YFP mice by two-photon microscopy. The bright green signals indicate CD11c-YFP–positive cells (DCs), and blue signals indicate collagen fibers in the skin. Vehicle was administered intravenously at 60 min. The timing of vehicle administration is indicated at the top left. DCs show an active random motion during the observation (time lapse over 240 min; 240 frames, 30 frames/s). Bar, 200 µm. Data are representative of three independent experiments with reproducible results.
