Video 2.

Time-lapse confocal imaging of a Tg(flk:GFP) embryo injected with A_2b MO. This video shows time-lapse spinning disk confocal imaging of the AGM region of an flk1:GFP embryo injected with A_2b MO between 32 and 44 hpf (1 frame/5 min). Numbers appear in the video to point to endothelial cells that initiate EHT and then fragment. Select frames of the video are shown in Fig. 5 B.

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

Lili Jing, Owen J. Tamplin, Michael J. Chen, Qing Deng, Shenia Patterson, Peter G. Kim, Ellen M. Durand, Ashley McNeil, Julie M. Green, Shinobu Matsuura, Julien Ablain, Margot K. Brandt, Thorsten M. Schlaeger, Anna Huttenlocher, George Q. Daley, Katya Ravid, and Leonard I. Zon

DOI: 10.1084/jem.20141528