Random NK cell migration within a collagen gel matrix. Representative DIC microscopy of NK cells from WT or Dock8-deficient mice, after expansion in IL-2. Note elongation of Dock8-deficient NK cells (red arrows).
Qian Zhang, Christopher G. Dove, Jyh Liang Hor, Heardley M. Murdock, Dara M. Strauss-Albee, Jordan A. Garcia, Judith N. Mandl, Rachael A. Grodick, Huie Jing, Devon B. Chandler-Brown, Timothy E. Lenardo, Greg Crawford, Helen F. Matthews, Alexandra F. Freeman, Richard J. Cornall, Ronald N. Germain, Scott N. Mueller, and Helen C. Su