Video 1.

Random T cell migration within a collagen gel matrix. Representative diffusion interference contrast (DIC) microscopy of T cells from a healthy control or DOCK8-deficient patient. Note elongation of patient T cells (red arrows) and spontaneous recovery in some cells.

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity

Qian Zhang, Christopher G. Dove, Jyh Liang Hor, Heardley M. Murdock, Dara M. Strauss-Albee, Jordan A. Garcia, Judith N. Mandl, Rachael A. Grodick, Huie Jing, Devon B. Chandler-Brown, Timothy E. Lenardo, Greg Crawford, Helen F. Matthews, Alexandra F. Freeman, Richard J. Cornall, Ronald N. Germain, Scott N. Mueller, and Helen C. Su

DOI: 10.1084/jem.20141307