Video 4.

Neutrophils recruited to the developing thrombus. GFP⁺ cells (green) in LysM-eGFP are also stained by a PE-labeled anti-Ly6G antibody (red), indicating neutrophils (yellow; video still in Fig. 3 F). Thrombus in the IVC 6 h after DVT induction visualized by two-photon microscopy is presented in a 3D rendering (frame rate: 5.03 frames/s).

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

Marie-Luise von Brühl, Konstantin Stark, Alexander Steinhart, Sue Chandraratne, Ildiko Konrad, Michael Lorenz, Alexander Khandoga, Anca Tirniceriu, Raffaele Coletti, Maria Köllnberger, Robert A. Byrne, Iina Laitinen, Axel Walch, Alexander Brill, Susanne Pfeiler, Davit Manukyan, Siegmund Braun, Philipp Lange, Julia Riegger, Jerry Ware, Annekathrin Eckart, Selgai Haidari, Martina Rudelius, Christian Schulz, Katrin Echtler, Volker Brinkmann, Markus Schwaiger, Klaus T. Preissner, Denisa D. Wagner, Nigel Mackman, Bernd Engelmann, and Steffen Massberg

DOI: 10.1084/jem.20112322