Video 12.

Effect of ablation of VLA-3 integrin on leukocyte extravasation. MP-IVM showed that the increase in the velocity of the head and tail mobility and the elongation at the extravascular area were inhibited in CXCL2-stimulated venules in Gr1-stained VLA-3–cKO mice. This video is shown at 10 frames/s.


Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels

Young-Min Hyun, Ronen Sumagin, Pranita P. Sarangi, Elena Lomakina, Michael G. Overstreet, Christina M. Baker, Deborah J. Fowell, Richard E. Waugh, Ingrid H. Sarelius, and Minsoo Kim

DOI: 10.1084/jem.20111426
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