Video 1.

In vitro killing of L. major parasites by GR1⁺ monocytes. GR1⁺ monocytes were sorted from CX3CR1^GFP/+ RAG2^−/− mice and plated on culture dishes. L. major parasites were added in the presence of 5% C5-deficient serum. Parasites were visualized on an inverted microscope 1 h later. Playback speed is 10× and the magnification is 400×. This movie is representative of 2 independent experiments using a total of 20 mice.

Platelet activation attracts a subpopulation of effector monocytes to sites of Leishmania major infection

Ricardo Goncalves, Xia Zhang, Heather Cohen, Alain Debrabant, and David M. Mosser

DOI: 10.1084/jem.20101751