Video 1.

Control and DOCK2-/- T cell migration in PLNs. T cells were purified from lymph nodes and spleens of control and DOCK2-deficient mice, labeled with CMTMR and CFSE, respectively, and injected into wild-type recipients 22 h before imaging. Second harmonic signals from collagen fibers are shown in blue. Time in minutes and seconds. Bar, 30 µm.


A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate–mediated egress

César Nombela-Arrieta , Thorsten R. Mempel , Silvia F. Soriano , Irina Mazo , Matthias P. Wymann , Emilio Hirsch , Carlos Martínez-A. , Yoshinori Fukui , Ulrich H. von Andrian , and Jens V. Stein

DOI: 10.1084/jem.20061780
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