Video 15.

A migrating DPEGFPxOT-I effector CTL initiating firm contact with a tissue macrophage. As described in Fig. 8, T cells (green, track) engaging in interactions with macrophages (cyan) were captured with two-photon microscopy. The macrophage is identified by the presence of autofluorescent particles within its cytoplasm. The time is indicated on the top margin (min:sec).


Random migration precedes stable target cell interactions of tumor-infiltrating T cells

Paulus Mrass , Hajime Takano , Lai Guan Ng , Sachin Daxini , Marcio O. Lasaro , Amaya Iparraguirre , Lois L. Cavanagh , Ulrich H. von Andrian , Hildegund C.J. Ertl , Philip G. Haydon , and Wolfgang Weninger

DOI: 10.1084/jem.20060710
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