Overall morphology of receptor-mediated mitophagy in the early phase, as revealed by electron tomography (related to Fig. 3, A–D). DRP1 KO HeLa cells were treated with DFP for 16 h and fixed with a mixture of aldehyde and osmium solutions for electron tomography. Serial EM images (115 sections) corresponding to Fig. 3 A are shown first, followed by color-segmented 3D reconstructed image (corresponding to Fig. 3, B–D) featuring a mitochondrion (pink), ER (blue), linear structures (cyan), an IM (green), and Golgi complex (pale yellow).