Deformation-resistant nuclei display enhanced dispersion and sphericity. Live imaging of embryos expressing RFP:NLS (false-colored green) and Spider:GFP (magenta) in wildtype control (left) and kuk disrupted (right) embryo. Note that fewer nuclei are in a common plane in kuk embryos. Frames are acquired every 15 s and the movie is played at 20 frames per second. Scale bar = 10 μm.