G3Ia and G3Ib, but not their inactive enantiomers, dissolve stress granules induced by heat stress. Live cell imaging of U2OS G3BP1-GFP-expressing cells following exposure to a 43°C heat shock for 30 min followed by treatment with 50 μM G3Ia, G3Ia′, G3Ib, or G3Ib′ (left to right) 25 min after exposure to heat shock. Playback speed: 5 frames per second.
