G3Ia and G3Ib, but not their inactive enantiomers, dissolve stress granules induced by sodium arsenite. Live cell imaging of U2OS G3BP1-GFP-expressing cells following exposure to 250 μM NaAsO2 for 30 min followed by treatment with 50 μM G3Ia, G3Ia′, G3Ib, or G3Ib′ (left to right). Playback speed: 3 frames per second.
