EGF endosomes undertake large movements toward the nucleus. HeLa cell after uptake of A647-tagged EGF (magenta) imaged using HILO microscopy over an ∼17-min time period. “N” marks the position/direction of the nucleus. Imaged at 2 fps, movie playback 100 fps. Scale bar: 5 µm. Movie related to Fig. 6, e–h.
