Video 3.

Actin dynamics in PtdIns(3,4)P₂-depleted macrophages during phagocytosis. Actin dynamics in RAW 264.7 macrophages expressing LifeAct-GFP (green) and INPP4B-CAAX constructs upon binding to SRBCs (red). Similar results were observed in at least three separate experiments. Frame rate, 10.00 frames/s.

PtdIns(3,4)P2, Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages

Fernando Montaño-Rendón, Glenn F.W. Walpole, Matthias Krause, Gerald R.V. Hammond, Sergio Grinstein, and Gregory D. Fairn

DOI: 10.1083/jcb.202207042