Video 4.

Super-resolution SIM of inter-lysosomal untethering event marked by mitochondria. Super-resolution time-lapse SIM of inter-lysosomal untethering event marked by mitochondria in a live HeLa cell expressing Lamp1-mGFP (lysosome; green) and mApple-TOM20 (mitochondria; red). Video was acquired at 1 frame/7 s for 105 s and played back at 4 frames/s (28× speed). Video corresponds to Fig. 2 C. Scale bar, 0.5 µm.


Mid51/Fis1 mitochondrial oligomerization complex drives lysosomal untethering and network dynamics

Yvette C. Wong, Soojin Kim, Jasmine Cisneros, Catherine G. Molakal, Pingping Song, Steven J. Lubbe, and Dimitri Krainc

DOI: 10.1083/jcb.202206140
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