Video 2.

TrkB-GFP movements upon cAMP stimulation within axon terminals of LV-mCh Smn−/−;SMN2 motoneurons. Time-laps videos were recorded from DIV7 Smn−/−;SMN2 motoneurons co-transduced with LV-mCh and LV-TrkB-GFP (gray) during a 30 min 100 µM 8-CPT-cAMP stimulation using an epifluorescence microscope acquiring images at a 2.5 s interval over a time period of 10 min. TrkB-GFP movements (gray) are shown at a display rate of 7 frames per second.


Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy

Luisa Hennlein, Hanaa Ghanawi, Florian Gerstner, Eduardo Palominos GarcĂ­a, Ezgi Yildirim, Lena Saal-Bauernschubert, Mehri Moradi, Chunchu Deng, Teresa Klein, Silke Appenzeller, Markus Sauer, Michael Briese, Christian Simon, Michael Sendtner, and Sibylle Jablonka

DOI: 10.1083/jcb.202204113
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