Video 6.

Example of mitotic outcome of a cell with an ensheathed chromosome. GSK923295-pretreated RPE-1 cell expressing GFP-Sec61β (green) stained with SiR-DNA (red). Cell has an ensheathed chromosome and missegregates, leading to a micronucleus. Time, hh:mm. Playback, 8 fps.


Endomembranes promote chromosome missegregation by ensheathing misaligned chromosomes

Nuria Ferrandiz, Laura Downie, Georgina P. Starling, and Stephen J. Royle

DOI: 10.1083/jcb.202203021
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