Video 2.

BCR clustering in INPP5BDegron/Degron cells stimulated on glass coverslips presenting surrogate antigen. Related to Fig. 1. Vehicle- or auxin-treated INPP5BDegron/Degron cells, prelabeled for BCR, were imaged by TIRF microscopy during their interaction with antibody-coated coverslips. The video is displayed at 100 frames/s. Scale bar, 10 μm.


The inositol 5-phosphatase INPP5B regulates B cell receptor clustering and signaling

Alaa Droubi, Connor Wallis, Karen E. Anderson, Saifur Rahman, Aloka de Sa, Taufiq Rahman, Len R. Stephens, Philip T. Hawkins, and Martin Lowe

DOI: 10.1083/jcb.202112018
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