Video 1.

Live primary mouse cortical neurons at day in vitro 11 (D11) expressing EGFP-LifeAct and pLKO-shRNA-TurboRFP targeting Enah, Evl, or non-targeting (n.t.) as indicated. Left: segment of dendrite with overlay of brightfield and intensity-coded LUT of EGFP-LifeAct. Right: EGFP-LifeAct alone. Scale bar = 10 µm. 5 s interval, 5 min duration, 10 fps. See also Fig. 1 and Fig. S2.

EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons

Sara S. Parker, Kenneth Tran Ly, Adam D. Grant, Jillian Sweetland, Ashley M. Wang, James D. Parker, Mackenzie R. Roman, Kathylynn Saboda, Denise J. Roe, Megha Padi, Charles W. Wolgemuth, Paul Langlais, and Ghassan Mouneimne

DOI: 10.1083/jcb.202106081