Video 2.

JAM-A localizes to membrane protrusions in HEK293T cells. Confocal laser scanning microscopy time lapse movie of Hek293T cells expressing JAM-A/EGFP. Z-stacks were taken every 2 min over a time period of 54 min. Note the accumulation of JAM-A/EGFP in ruffle-like protrusions. Scale bar: 10 µm.

A JAM-A–tetraspanin–αvβ5 integrin complex regulates contact inhibition of locomotion

Daniel Kummer, Tim Steinbacher, Sonja Thölmann, Mariel Flavia Schwietzer, Christian Hartmann, Simone Horenkamp, Sabrina Demuth, Swetha S.D. Peddibhotla, Frauke Brinkmann, Björn Kemper, Jürgen Schnekenburger, Matthias Brandt, Timo Betz, Ivan Liashkovich, Ivan U. Kouzel, Victor Shahin, Nathalie Corvaia, Klemens Rottner, Katsiaryna Tarbashevich, Erez Raz, Lilo Greune, M. Alexander Schmidt, Volker Gerke, and Klaus Ebnet

DOI: 10.1083/jcb.202105147