Video 9.

Time-lapse confocal imaging of gastrula-stage Xenopus embryo illustrates the increased frequency of Rho flares (mCherry-2xrGBD, grayscale) in embryos treated with 12.5 µM GsMTx4 (green arrowheads) compared with vehicle control (yellow arrows). Dividing cells are marked by cyan asterisks. Time interval, 21 s; video frame rate, 20 fps. Related to Fig. 7 C.


Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling

Saranyaraajan Varadarajan, Shahana A. Chumki, Rachel E. Stephenson, Eileen R. Misterovich, Jessica L. Wu, Claire E. Dudley, Ivan S. Erofeev, Andrew B. Goryachev, and Ann L. Miller

DOI: 10.1083/jcb.202105107
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