Video 2.

Time-lapse confocal imaging of gastrula-stage Xenopus embryo shows the calcium (mNeon-C2, green) increases locally at sites of Rho flares (mCherry-2xrGBD, magenta) during cell shape changes. Time interval, 10 s; video frame rate, 20 fps. Related to Fig. 1, C and D.


Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling

Saranyaraajan Varadarajan, Shahana A. Chumki, Rachel E. Stephenson, Eileen R. Misterovich, Jessica L. Wu, Claire E. Dudley, Ivan S. Erofeev, Andrew B. Goryachev, and Ann L. Miller

DOI: 10.1083/jcb.202105107
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