Video 2.

Time-lapse confocal fluorescence microscopy of an α-catenin KD MEF expressing mCherry-α-actinin (magenta) and WT GFP-α-catenin (green). Images were acquired every 30 s for 36.5 min. Playback, 20 fps.

α-Catenin links integrin adhesions to F-actin to regulate ECM mechanosensing and rigidity dependence

Abhishek Mukherjee, Shay Melamed, Hana Damouny-Khoury, Malak Amer, Lea Feld, Elisabeth Nadjar-Boger, Michael P. Sheetz, and Haguy Wolfenson

DOI: 10.1083/jcb.202102121