Video 5.

Tomogram of MVB in a bro1Δ cell expressing Bro1^M8. This tomogram depicts one MVBs in a bro1Δ cell expressing Bro1^M8. This MVB contains several budding intermediates (green), while its limiting membrane is shown in yellow and ILVs are labeled red. Scale bar = 100 nm. Frame rate, 50 frames/s.

Bro1 stimulates Vps4 to promote intralumenal vesicle formation during multivesicular body biogenesis

Chun-Che Tseng, Shirley Dean, Brian A. Davies, Ishara F. Azmi, Natalya Pashkova, Johanna A. Payne, Jennifer Staffenhagen, Matt West, Robert C. Piper, Greg Odorizzi, and David J. Katzmann

DOI: 10.1083/jcb.202102070