Video 6.

MyD88-GFP dynamics in WT, IRAK4 KO, and IRAK1 KO EL4 cells (related to Fig. 6). This video shows MyD88-GFP in WT (left), IRAK1 KO (middle), and IRAK4 KO (right) EL4 cells landing on an IL1β-functionalized supported lipid membranes. White box in each panel indicates example cells shown in Fig. 6 A. Scale bar, 5 µm.

MyD88 oligomer size functions as a physical threshold to trigger IL1R Myddosome signaling

Rafael Deliz-Aguirre, Fakun Cao, Fenja H.U. Gerpott, Nichanok Auevechanichkul, Mariam Chupanova, YeVin Mun, Elke Ziska, and Marcus J. Taylor

DOI: 10.1083/jcb.202012071