Early phase of simulation of LAT cluster formation at intermediate PLCγ1-to-LAT ratio. The simulation involves 200 LAT, 150 PLCγ1, 400 Grb2, and 200 Sos1 molecules, all in a monomeric state. The simulation starts at second 2.00, corresponding to timestep 0, and ends at timestep 10 × 106. The interval between two frames is 0.2 × 106 timesteps, and the frame rate is 8 s−1. Particle scheme is the same as in Fig. 6 A: gray, LAT; yellow, PLCγ1; blue, Grb2; and pink, Sos1.
