Video 1.

HSPC migration in a bone-marrow-on-a-chip. Video shows transmitted light (phase contrast) of an HSPC loaded in the central channel and migrating toward the pseudo-endosteal compartment (top channel), containing osteoblasts, and the pseudo-vascular compartment (bottom channel), containing endothelial cells, forming a vascular network. The pitch of central pilar spacing is 200 µm. Time is indicated in hours.


Hematopoietic progenitors polarize in contact with bone marrow stromal cells in response to SDF1

Thomas Bessy, Adrian Candelas, Benoit Souquet, Khansa Saadallah, Alexandre Schaeffer, Benoit Vianay, Damien Cuvelier, Samy Gobaa, Cecilia Nakid-Cordero, Julien Lion, Jean-Christophe Bories, Nuala Mooney, Thierry Jaffredo, Jerome Larghero, Laurent Blanchoin, Lionel Faivre, Stephane Brunet, and Manuel Théry

DOI: 10.1083/jcb.202005085
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