Video 7.

Tubulation of phagosomes containing mRFP1–E. coli. Macrophages were allowed to internalize mRFP1–E. coli, and imaging was started 180 min after phagocytosis. mRFP1-positive vesicles are pseudocolored to enhance visibility of low-intensity events. Images were acquired at 1 frame every 3 s. Playback rate is 2 frames/s. Still frames from Video 7 are displayed in Fig. 3 B. Scale bar: 2 µm.


Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes

Charlene E. Lancaster, Aaron Fountain, Roaya M. Dayam, Elliott Somerville, Javal Sheth, Vanessa Jacobelli, Alex Somerville, Mauricio R. Terebiznik, and Roberto J. Botelho

DOI: 10.1083/jcb.202005072
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