Video 5.

Dynamics of growth cones in control and APC-depleted neurons. Time-lapse microscopy of DIV6 hippocampal neurons infected at DIV1 with lentiviruses carrying mCherry-F-tractin and either nontargeting (control) or APC-targeting (APCsh1) shRNA. Scale bar, 10 µm.


Branched actin networks are assembled on microtubules by adenomatous polyposis coli for targeted membrane protrusion

Nadia Efimova, Changsong Yang, Jonathan X. Chia, Ning Li, Christopher J. Lengner, Kristi L. Neufeld, and Tatyana M. Svitkina

DOI: 10.1083/jcb.202003091
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