Video 5.

hNK cells activate caspase in invading tumor cells. Live confocal imaging of hNK cells (red) interacting with invading tumor cells (blue, circled), leading to activation of caspase (green) in tumor cells. Scale bar, 20 µm. Video frame rate is 10 frames per second.


Cancer cells educate natural killer cells to a metastasis-promoting cell state

Isaac S. Chan, Hildur Knútsdóttir, Gayathri Ramakrishnan, Veena Padmanaban, Manisha Warrier, Juan Carlos Ramirez, Matthew Dunworth, Hao Zhang, Elizabeth M. Jaffee, Joel S. Bader, and Andrew Josef Ewald

DOI: 10.1083/jcb.202001134
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