Video 2.

Local calcium influx in axons, not in soma by dimerization of MLKL.ND. Live-cell images of WT and SARM1 KO neurons cultured in microfluidic devices. BB is only applied to the axon compartment. Images were acquired every 1 h.


SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration

Kwang Woo Ko, Jeffrey Milbrandt, and Aaron DiAntonio

DOI: 10.1083/jcb.201912047
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