Video 2.

MLF2-GFP foci localize to NE membranes. Z scan through recently divided 4TorKO cells expressing mScarlet-Sec61B and MLF2-GFP. The majority of MLF2-GFP foci form on the NE and its membranous protrusions extending into the nucleus. Video corresponds to Fig. 5 B. Video display rate is 7 fps.

Torsin ATPase deficiency leads to defects in nuclear pore biogenesis and sequestration of MLF2

Anthony J. Rampello, Ethan Laudermilch, Nidhi Vishnoi, Sarah M. Prophet, Lin Shao, Chenguang Zhao, C. Patrick Lusk, and Christian Schlieker

DOI: 10.1083/jcb.201910185