Video 1.

Computer simulation of the interaction between the LMX1B peptide and LC3B. Movie of an example computer simulation of the LMX1B–LC3B interaction (relates to Fig. S3 A). The LMX1B peptide motif was docked by molecular replacement in the position adopted by the FYCO1 LIR (5d94.pdb). LC3B is shown in cyan; LMX1B LIR in magenta. The movie spans 50 ns.


ATG8-dependent LMX1B-autophagy crosstalk shapes human midbrain dopaminergic neuronal resilience

Natalia Jiménez-Moreno, Madhu Kollareddy, Petros Stathakos, Joanna J. Moss, Zuriñe Antón, Deborah K. Shoemark, Richard B. Sessions, Ralph Witzgall, Maeve Caldwell, and Jon D. Lane

DOI: 10.1083/jcb.201910133
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