Video 4.

Time-lapse epifluorescence of a HeLa FlpIn cell expressing GFP-MPS1^DD filmed through mitosis. Related to Fig. 4 A, bottom panel. DNA (SiR-Hoechst) is shown in red and GFP-MPS1 in cyan. Images were captured once every 2 min. 0 min = nuclear envelope breakdown. Video is displayed at 7 frames per second.

Checkpoint signaling and error correction require regulation of the MPS1 T-loop by PP2A-B56

Daniel Hayward, James Bancroft, Davinderpreet Mangat, Tatiana Alfonso-Pérez, Sholto Dugdale, Julia McCarthy, Francis A. Barr, and Ulrike Gruneberg

DOI: 10.1083/jcb.201905026