Video 3.

Microtubule dynamics at FAs in migrating cells. Related to Fig. 5. Representative examples of time-lapse TIRF imaging of microtubules (3xGFP-EMDB, cyan) and FAs (mCherry-zyxin, pink) in migrating MDA-MB-231 cells ectopically expressing full-length APC-WT or APC-m4, as indicated. Images were acquired every 5 s. Video is shown at seven frames per second. Scale bar, 5 µm.


The role of APC-mediated actin assembly in microtubule capture and focal adhesion turnover

M. Angeles Juanes, Daniel Isnardon, Ali Badache, Sophie Brasselet, Manos Mavrakis, and Bruce L. Goode

DOI: 10.1083/jcb.201904165
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