Video 1.

FA dynamics in migrating cells. Related to Fig. 4. Representative examples of time-lapse TIRF imaging of FAs (mCherry-zyxin, pink) in migrating MDA-MB-231 cells ectopically expressing APC-WT or APC-m4, as indicated. Yellow boxes that appear during the video highlight the same four FAs shown as examples in Fig. 4, A and B. Images were acquired every 10 s. Video is shown at seven frames per second. Scale bar, 10 µm.


The role of APC-mediated actin assembly in microtubule capture and focal adhesion turnover

M. Angeles Juanes, Daniel Isnardon, Ali Badache, Sophie Brasselet, Manos Mavrakis, and Bruce L. Goode

DOI: 10.1083/jcb.201904165
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