Colchicine and Taxol disrupt mesoderm invagination but does not interfere with apical constriction initiation. Embryos expressing Myo::GFP (green) and Gap43::mCH (magenta) were injected with DMSO (top), colchicine (5 mg/ml; middle), or Taxol (5 mg/ml; bottom). Images were acquired every 6.4 s, and videos are displayed at 15 frames per second. Scale bars, 15 µm.
