Video 4.

Localization (left) and activity map (right) of RhoA biosensor in motile MDA-MB-231 cells. Duration: 12.9 min. 7 FPS. Scale bar = 10 µm.

Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways

Mihai L. Azoitei, Jungsik Noh, Daniel J. Marston, Philippe Roudot, Christopher B. Marshall, Timothy A. Daugird, Sidney L. Lisanza, María-José Sandí, Mitsu Ikura, John Sondek, Robert Rottapel, Klaus M. Hahn, and Gaudenz Danuser

DOI: 10.1083/jcb.201812073