Video 2.

Invadopodia are more transient in cells expressing increased levels of MTCBP-1. BxPC3 cells stably expressing MTCBP-1-FLAG were transiently transfected with TKS5-GFP and subjected to live-cell imaging on gelatin-coated imaging dishes for 16 h and 40 min at 5 min intervals.


Pancreatic tumor cell metastasis is restricted by MT1-MMP binding protein MTCBP-1

Li Qiang, Hong Cao, Jing Chen, Shaun G. Weller, Eugene W. Krueger, Lizhi Zhang, Gina L. Razidlo, and Mark A. McNiven

DOI: 10.1083/jcb.201802032
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